Cart
sales@molnova.com
PSB 1115
CAS No. 152529-79-8
PSB 1115( —— )
Catalog No. M27689 CAS No. 152529-79-8
PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1602 | Get Quote |
|
| 10MG | 2151 | Get Quote |
|
| 25MG | 3222 | Get Quote |
|
| 50MG | 4347 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePSB 1115
-
NoteResearch use only, not for human use.
-
Brief DescriptionPSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.
-
DescriptionPSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.(In Vitro):PSB 1115 reversed the decrease in plasma insulin induced by NECA.(In Vivo):The effect of PSB 1115 was obvious in diabetic GotoKakizaki rats: plasma insulin was increased whereas blood glucose was unchanged. The adenosine levels were not different in normal Wistar rats and in diabetic GotoKakzaki rats.
-
In Vitro——
-
In VivoPSB-1115 (0.5 mg/kg; i.p.; single dose, 20 min before the inhalation) antagonizes the inhibitory effect of non-selective adenosine receptor agonist NECA (HY-103173) on mucociliary clearance in mice.
-
Synonyms——
-
PathwayApoptosis
-
TargetAdenosine Receptor
-
RecptorPEGs|Alkyl/ether
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number152529-79-8
-
Formula Weight350.35
-
Molecular FormulaC14H14N4O5S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(O)(=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
molnova catalog
related products
-
Binodenoson
Binodenoson is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging.
-
Regadenoson
Regadenoson is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity.
-
CHEMBL241987
CHEMBL241987 targets the Adenosine receptor A3 (human).
