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PSB 1115
CAS No. 152529-79-8
PSB 1115( —— )
Catalog No. M27689 CAS No. 152529-79-8
PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1602 | Get Quote |
|
| 10MG | 2151 | Get Quote |
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| 25MG | 3222 | Get Quote |
|
| 50MG | 4347 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePSB 1115
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NoteResearch use only, not for human use.
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Brief DescriptionPSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.
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DescriptionPSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.(In Vitro):PSB 1115 reversed the decrease in plasma insulin induced by NECA.(In Vivo):The effect of PSB 1115 was obvious in diabetic GotoKakizaki rats: plasma insulin was increased whereas blood glucose was unchanged. The adenosine levels were not different in normal Wistar rats and in diabetic GotoKakzaki rats.
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In Vitro——
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In VivoPSB-1115 (0.5 mg/kg; i.p.; single dose, 20 min before the inhalation) antagonizes the inhibitory effect of non-selective adenosine receptor agonist NECA (HY-103173) on mucociliary clearance in mice.
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Synonyms——
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PathwayApoptosis
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TargetAdenosine Receptor
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RecptorPEGs|Alkyl/ether
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Research Area——
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Indication——
Chemical Information
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CAS Number152529-79-8
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Formula Weight350.35
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Molecular FormulaC14H14N4O5S
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(O)(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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